刘秀秀,博士,副教授。2020年博士毕业于浙江大学澳门威斯人0168药理学专业。主要从事神经精神疾病的分子机制及药物靶标研究,包括自发性癫痫、焦虑、自闭、小脑性共济失调等,相关研究成果发表于国际知名期刊Journal of Experimental Medicine、Signal Transduction and Targeted Therapy、Molecular Psychiatry等杂志。主持国家自然科学基金青年项目、江苏省自然科学基金青年项目、中国博士后科学基金等多项科研项目。
研究方向:神经精神疾病的分子机制及药物靶标研究
联系方式:E-mail: xiuxiuliu@njmu.edu.cn
教育背景及工作经历:
2022.10-至今 南京医科大学 澳门威斯人0168 副教授
2020.07-2022.06 南京医科大学 澳门威斯人0168 博士后
2015.09-2020.06 浙江大学 澳门威斯人0168 药理学博士
2010.09-2015.06 哈尔滨医科大学 澳门威斯人0168 本科
承担科研项目情况:
1.国家自然科学基金青年项目,82104162,2022/01-2024/12,30万元,在研,主持
2.江苏省自然科学基金青年项目,BK20210539,2021.07-2024.06,24万元,在研,主持
学术任职:
1.《中国药理学通报》青年编辑委员会委员
2.《Medicine Advances》青年编辑委员会委员
3.心脑血管药理专业委员会第二届青年委员会委员
4.微循环药物研究专委会委员
5.中国药理学会生化与分子药理学专业委员会第二届青年委员会委员
代表性论文:
1. Xiu-Xiu Liu#, Xing-Hui Chen, Zhi-Wei Zheng, Qin Jiang, Chen Li, Lin Yang, Xiang Chen, Xing-Feng Mao, Hao-Yang Yuan, Li-Li Feng, Quan Jiang, Wei-Xing Shi, Takuya Sasaki, Kohji Fukunaga, Zhong Chen, Feng Han*, Ying-Mei Lu*; BOD1 regulates the cerebellar IV/V lobe-fastigial nucleus circuit associated with motor coordination, Signal Transduction and Targeted Therapy, 2022 Jun 1;7(1):170. doi: 10.1038/s41392-022-00989-x.
2. Xiu-Xiu Liu#; Lin Yang#; Ling-Xiao Shao#; Yang He; Gang Wu; Yu-Huan Bao; Nan-Nan Lu; Dong-Mei Gong; Ya-Ping Lu; Tian-Tian Cui; Ning-He Sun; Dan-Yang Chen; Wei-Xing Shi; Kohji Fukunaga; Hong-Shan Chen; Zhong Chen*; Feng Han*; Ying-Mei Lu*; Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis, Journal of Experimentl Medicine, 2020, 217(1): 0-e20180992.
3. Ling-Xiao Shao#; Quan Jiang#; Xiu-Xiu Liu#; Dong-Mei Gong; Yi-Xuan Yin; Gang Wu; Ning-He Sun; Cheng-Kun Wang; Qiao-Zhen Chen; Chao Yu; Wei-Xing Shi; Heng-Yu Fan; Kohji Fukunaga; Zhong Chen; Ying-Mei Lu*; Feng Han*; Functional coupling of Tmem74 and HCN1 channels regulates anxiety-like behavior in BLA neurons, Molecular Psychiatry, 2019, 24(10): 1461-1477.
4. Ya-Ping Lu#, Xiang Chen, Xiu-Xiu Liu, Yi Shi, Zhao-Cong Wei, Li-Li Feng, Quan Jiang, Wei-Feng Ye, Takuya Sasaki, Kohji Fukunaga, Yong Ji, Feng Han, Ying-Mei Lu, Endothelial TFEB signaling-mediated autophagic disturbance initiates microglial activation and cognitive dysfunction, Autophagy, 2023, Jan 1;1-18.
5. Zheng-Mao Li#; Xiu-Xiu Liu#; Chen Li; Zhao-Cong Wei; Yi Shi; Heng-Yi Song; Xiang Chen; Yu Zhang; Jia-Wei Li; Rui-Fang Zhu; Ben-Hui Hu; Wei-Feng Ye; Da Huo; Guo-Jun Jiang; Takuya Sasaki; Li Zhang; Feng Han*; Ying-Mei Lu*; Decreased synapse-associated proteins are associated with the onset of epileptic memory impairment in endothelial CDK5-deficient mice, Medcomm, 2022
6. Gang Wu#; Xiu-Xiu Liu#; Nan-Nan Lu; Qi-Bing Liu; Yun Tian; Wei-Feng Ye; Guo-Jun Jiang; Rong-Rong Tao; Feng Han*; Ying-Mei Lu*; Endothelial ErbB4 deficit induces alterations in exploratory behavior and brain energy metabolism in mice, CNS Neuroscience & Therapeutics, 2017, 23(6): 510-517.