陈立娜

发布时间:2020-07-01浏览次数:7424

陈立娜,党员,南京医科大学教授,博士生导师,药物分析学系主任,中药发展办公室主任,校优秀中青年学科(学术)带头人。国家自然科学基金网评专家,江苏省高校青蓝工程优秀青年骨干教师培养人选,教育部学位与研究生教育发展中心专家,中国医药生物技术协会药物分析技术分会常务委员,江苏省药学会药物分析专业委员会委员,中国民族医药学会药理与病理学分会理事,中国中医药信息学会科技创新与成果转化分会理事,中华中医药学会中药分析学会理事。

近年来,主要围绕现代分析技术在药物研究中的应用和脑卒中等重大疾病治疗药物的发现等方面的研究,先后主持国家自然科学基金项目3项,江苏省科技厅科技计划项目1项,中国博士后科学基金1项,江苏省教育厅自然科学基金2项,南医大-苏盐智慧健康科技创新研发资金项目1项,校级课题5项。作为主要参加人员参与国家863计划项目1项,国家自然科学基金项目3项。在Journal of Cleaner ProductionJournal of Nanobiotechnology等国内外主要期刊发表研究论文50余篇。以第一作者身份获授权国家发明专利9件,主编或参编 “十二五”、“十三五”“十规划教材9

招生方向:1.现代药物分析2.药学

联系方式:chenlina@njmu.edu.cn

代表性论文:

1.Shuzhen Wang,Jiaye Wang,Yuan Yao,Jia-Yan Liu,Yankun Gao,Qiaoli Hua,Qingcai Jiao,Junzhong Liu,Yang Jin*,Hongjuan Zhang*,Lina Chen*.A mild one-pot self-assembly approach to encapsulating enzymes into metal-organic framework with Asp-boosted enzymatic performance for clean production, Journal of Cleaner Production,2023,401:136710

2. Yingying Ding,Yang Jin,Tao Peng,Yankun Gao,Yang Zang,Hongliang He,Fei Li,Yu Zhang*,Hongjuan Zhang*, Lina Chen*.Fabrication of multifunctional metal–organic frameworks nanoparticles via layer-by-layer self-assembly to efficiently discover PSD95-nNOS uncouplers for stroke treatment, Journal of Nanobiotechnology,2022,20:379

3. Hongliang He#, Min Cao#, Jingwan Hu, Ling Zhu, Chang Su, Shuhu Du, Jian Yang*, Yulin Tang*, Lina Chen*. Fluorescent turn-on assay of C-type natriuretic peptide using a molecularly imprinted ratiometric fluorescent probe with high

selectivity and sensitivity, Microchimica Acta,2020,187(11):614

4. Linli Pan, Yingying Ding, Xiaoting Ni, Chong-Zhi Wang, Bo Jiang, Yu Zhang, Nan Jiang, Yulin Tang, Lina Chen*, Chun-Su Yuan. Modeling rapid and selective capture of nNOS–PSD-95 uncouplers from Sanhuang Xiexin decoction by novel molecularly imprinted polymers based on metal-organic frameworks, RSC Advances, 2020,10:7671-7681

5.Chenghong Sun, Linli Pan, Lei Zhang, Jiaojiao Huang,Dandan Yao,Chong-Zhi Wang,Yu Zhang, Nan Jiang, Lina Chen *,Chun-Su Yuan. A biomimetic fluorescent nanosensor based on imprinted polymers modified with carbon dots for sensitive detection of alpha-fetoprotein in clinical samples, Analyst, 2019,144:6760-6772.

6.Jiaojiao Huang, Chenghong Sun,Dandan Yao, Chong-Zhi Wang,Lei Zhang,Yu Zhang, Lina Chen *,Chun-Su Yuan. Novel surface imprinted magnetic mesoporous silica as artificial antibodies for efficient discovery and capture of candidate nNOS–PSD-95 uncouplers for stroke treatment, Journal of Materials Chemistry B, 2018, 6:1531-1542.


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